Browsing by Author "Farouk, Faten"

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nvestigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies

Farouk, Faten; Abo Elmaaty, Ayman; Elkamhawy, Ahmed; Haytham O., Tawfik; Alnajjar, Radwan; S. Abourehab, Mohammed A.; Saleh, Mohamed A.; Eldehna, Wagdy M.; Al‐Karmalawy, Ahmed A. (2023-02-02)

Topoisomerase II (TOP-2) is a promising molecular target for cancer therapy. Numerous antibiotics could interact with biologically relevant macromolecules and provoke antitumor potential. Herein, molecular docking studies ...