Incidence rate of Multidrug-resistant Tuberculosis in Benghazi
| dc.contributor.author | Alobiedi, Abdelaziz Adel Abdelaziz Sultan | |
| dc.date.accessioned | 2020-09-21T11:11:57Z | |
| dc.date.available | 2020-09-21T11:11:57Z | |
| dc.date.issued | 2019 | |
| dc.identifier.uri | http://repository.limu.edu.ly/handle/123456789/1946 | |
| dc.description | Tuberculosis is caused by bacteria called mycobacterium tuberculosis. Worldwide, M. tuberculosis causes more deaths than any other single microbial agent. Mycobacterium tuberculosis differs from Atypical Mycobacteria in various ways. The most important difference is that the Mycobacterium tuberculosis is found only in humans, whereas atypical are found in the environment. (1,2) The atypical are also called “Mycobacteria other than M. tuberculosis,” or MOTTS. The atypical are subdivided into rapid growers and slow growers based on whether they form colonies in more than or less than 7 days. (1) The following are important slow growers: (1) Mycobacterium avium-intracellulare complex (MAC) causes tuberculosis-like disease, especially in immunocompromised patients, such as those with AIDS. It is highly antibiotic-resistant. (2) Mycobacterium kansasii also causes tuberculosis-like disease but is less antibiotic-resistant than MAC. (3) Mycobacterium marinum causes “swimming pool granuloma or fish tank granuloma,” which is a skin lesion at the site of an abrasion acquired in a swimming pool or an aquarium. (4) Mycobacterium scrofulaceum causes scrofula, which manifests as swollen, non-tender cervical lymph nodes (cervical adenitis). Mycobacterium avium-intracellulare complex (MAC) enters the human body from air droplet and become intracellular bacteria, mainly at the apical part of the lung. | en_US |
| dc.description.abstract | About one-third of the world’s population is infected with mycobacterium tuberculosis. Every year about 500,000 people worldwide are infected with multidrug- resistant Mycobacterium tuberculosis (MDR). The human bacteria that cause TB is called Mycobacterium avium-intracellulare complex (MAC), is enter The human body from air droplet and become intracellular bacteria, mainly at the apical part of the lung. The study aims to identify cases that develop MDR-MTB recently in Benghazi city and to change results from 9 years ago. A retrospective study has been conducted to identify the characteristic of pulmonary TB cases that admitted to Quefia Chest Hospital in Benghazi, Libya from (March) 2018 to (December) 2019. Results showed that 10 cases out of 352 TB patients were resistant to anti-TB drugs. comparing the results in 2009 and 2010 for the pulmonary TB cases that admitted to Quefia Chest Hospital Benghazi, Libya showed that 4 cases out of 430 TB patients were resistant to anti-TB drugs. The MDR-TB patient was positive for sensitivity culture and didn't respond to the first-line anti-TB therapy (isoniazid and rifampicin), the 2 most powerful anti-TB drugs and therefore were diagnosed as Multidrug- Resistant Tuberculosis (MDR-TB) | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | faculty of Basic Medical Science - Libyan International Medical University | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.title | Incidence rate of Multidrug-resistant Tuberculosis in Benghazi | en_US |
| dc.type | Other | en_US |
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