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Effect of SLE on kidneys

dc.contributor.authorlenghi, Dunia
dc.date.accessioned2020-09-26T11:32:44Z
dc.date.available2020-09-26T11:32:44Z
dc.date.issued2020-03-10
dc.identifier.urihttp://repository.limu.edu.ly/handle/123456789/1986
dc.descriptionSystemic lupus erythematosus (SLE) is an immune system disorder that comes about in incessant aggravation and harm of more than one organ. It is analyzed clinically and serologically with the nearness of autoantibodies.[1] "Lupus" is a Latin term meaning "wolf," since one of the trademark facial SLE rashes is comparative to the bitemark of a wolf [1] In this disorder , autoantibodies are directed against DNA, histones, nucleolar proteins, and other components of the cell core. Antibodies against double-stranded DNA are the hallmark of systemic lupus erythematosus. The disease influences basically females between the ages of 20 and 60 years. People with HLA-DR2 orDR3 qualities are inclined to systemic lupus erythematosusen_US
dc.description.abstractBackground :Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology, characterized by multi-organ inflammation and positive serum autoantibodies. Methods :Human tissues , urine samples have been used and circulating T cells and were assessed by flow cytometry in peripheral blood samples Results :Tissue damage associated with high levels of circulating T cells and elevate protein level in the urine Conclusion : Pathogenesis of LN such as generation of autoantibodies, secretion of proinflammatory and anti-inflammatory cytokines and abnormality of T lymphocytes, particularly the T-helper subsets, is also highly pertinent in the development of LN. Lupus nephritis (LN) is the foremost common and serious complication of SLEen_US
dc.language.isoenen_US
dc.publisherfaculty of Basic Medical Science - Libyan International Medical Universityen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.titleEffect of SLE on kidneysen_US
dc.typeOtheren_US


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Attribution 3.0 United States
Except where otherwise noted, this item's license is described as Attribution 3.0 United States