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Paroxysmal Nocturnal Hemoglobinuria

dc.contributor.authorMohamed, Salma Samir
dc.descriptionParoxysmal Nocturnal Hemoglobinuria is a very rare disease occurs in 1 every million worldwide. It hard to differentiate its symptoms from other overlapping conditions, and takes long time to be properly diagnosed.It is mainly caused by mutation in genes that code anchoring proteins on different blood cells types. The different symptoms mainly depends on intravascular hemolysis. The management aimed to correct the anemia and to prevent life-threatening conditions as thrombi and intravascular clottingen_US
dc.description.abstractParoxysmal Nocturnal Hemoglobinuria originates from mutant genes in stem cells of bone marrow that differentiate to different types of blood cells.Hemolytic anemia, bone marrow failure and thrombophilia is Clinical triad typical for PNH. The management depend on patient caseen_US
dc.publisherfaculty of Basic Medical Science - Libyan International Medical Universityen_US
dc.rightsAttribution 3.0 United States*
dc.titleParoxysmal Nocturnal Hemoglobinuriaen_US

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Except where otherwise noted, this item's license is described as Attribution 3.0 United States