Correlation Between Thyroid Dysfunctions and Pregnancy
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Date
2020-03-12
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
The thyroid diseases are the most common disorders that effect the women in
reproductive period due to several factors. However, if thyroid dysfunction is not
treated or delayed in diagnosis in early pregnancy, they will effect both mother and
fetus by sever outcomes. Moreover, the subclinical hypothyrodism is the most common
thyroid disorder in pregnancy. The rate of clinical hypothyroidism was 2.4%,
subclinical hypothyroidism was 11.3%, and 1.5% of pregnant women with overt
hyperthyroidism, and subclinical hyperthyroidism was 0.3%. Inaddition, the best
choice of treatment in pregnant women with hypothyrodism is a replacement therapy
with levothyroxine, while the propylthiouracil is preferred in hyperthyrodism
Description
Pregnancy is an important reproductive period, with reversible effects on thyroid gland
in pregnant women such as: thyroid function, size, and iodine metabolism, in addition,
the immune system changes can occur.
(1,5) If these changes are not detected and
untreated in early pregnancy, will lead to sever maternal and fetal outcomes.(2)
Estimation of thyroid diseases in pregnancy is essential for normal and healthy
gestational period, beacause the changes during pregnancy will lead to thyroid
dysfunction.(2,4) Furthermore, thyroid function tests such as Free Thyroxine (FT4), Free
triiodothyonine (FT3), thyroid-stimulating hormone (TSH), anti-thyroid peroxidase
antibodies (TPO), and measurement of iodine level in urine is important in early
diagnosis to prevent maternal and fetal complications
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