RELATION BETWEEN BRONCHITIS AND IMMUNOGLOBULIN
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Date
2020-03-12
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
The goal of the present study is to explore the physiological effects of
injected human immunoglobulin on patients with severe bronchiolitis
before and after treatment. 86 young children with severe bronchiolitis
were randomly divided into the observation group (43 cases) and the
treatment group (43 cases). On the basis of conventional therapy, the
children in the treatment group were given human immunoglobulin (400
mg/kg, 1–3 times) via intravenous injection. 60 healthy young children,
as determined by a physical examination given at the Zhumadian Central
Hospital, were enrolled as the control group. The T lymphocytes,
cytokines, IgA, IgG, and IgM immunoglobulins in the peripheral blood of
all 3 groups were measured. The clinical efficacy of the immunoglobulins
to mitigate the effects of bronchiolitis and the amount of time for the
reduction of symptoms to occur were observed
Description
Severe bronchiolitis is a lower respiratory tract infectious disease, a
common clinical acute and critical case in pediatrics, and the leading
cause of death among children, and it is more common in children less
than 2 y old. The main symptoms are recurrent wheezing, difficulty
breathing, thus causing hypoxia, endothelial damage, and platelet
activation leading to a hypercoagulable state..
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