Treatment of Cocaine Addiction with Viruses
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Date
2018-06-30
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
There are many pharmacological approaches and behavioral interventions that can
limit the addiction of cocaine, but with a small success. However, there are new
methods that have been studied over the past few years such as
immunopharmacotherapy that target cocaine molecules which is assisted by
adenoviruses, phage therapy, and the use of viral gene transfer of cocaine degrading
enzymes
Description
Cocaine is an extremely addictive drug that acts on the brain causing it to release
excessive levels of the neurotransmitter dopamine to produce a feeling of euphoria or
extreme pleasure. A number of medications acting as agonists, antagonists, or
antidepressants have been evaluated in both animal models and humans, with only
limited success. However, there is a new approach to treat cocaine dependence with
viruses. There are different ways to utilize viruses such as using Filamentous
bacteriophages that have anti-cocaine antibodies on their surfaces, Adenovirus-based
vaccine, and by viral gene transfer of butyrylcholinesterase.
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Except where otherwised noted, this item's license is described as Attribution 3.0 United States