The Disparity in Urine Output in Both Genders While Administering Lasix

Abstract

Introduction: Lasix is a common potent loop diuretic that had been used in the treating edematous states and increases the urine output; which is a relevant marker of renal function. Materials and methods: This study was done in double blind randomized control style, sample pool included 12 Subjects (6 females and 6 males), furosemide (Lasix) was administrated under clinically stable conditions for 6 hours; to measure their urine output, statistical analysis done by SPSS 26.0 using the two-sample t-test. Results: the analytic result shows that (p-value<0.05) p-value = 0.142, which is not significant; thus, we accept the null hypothesis. The furosemide has higher urine output in men rather than women despite the small sample size and assuming the subjects are in healthy status. Conclusion: in the current study, it is clear that furosemide affects the urine output which is a method of treating patients with severely oedematous conditions, and their wild consumption can lead to adverse effects in both genders.