Characteristics of brain in Autism Spectrum Disorder
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Date
2020-02-17
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder
characterized by impaired social communication and restricted and repetitive
behaviors (RRBs). Over the past decade, neuroimaging studies have provided
considerable insights underlying neurobiological mechanisms of ASD. In this review,
we introduce recent findings from brain imaging studies to characterize the brains of
ASD across the human lifespan. Results of structural Magnetic Resonance Imaging
(MRI) studies dealing with total brain volume, regional brain structure and cortical
area are summarized. Using task-based functional MRI (fMRI), many studies have
shown dysfunctional activation in critical areas of social communication and RRBs
Description
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
persistent deficits in social communication and restricted repetitive behaviors (RRBs).
The proportion of the adult population afflicted with ASD is estimated to be 2.4%–
9.9% childhood autism is broadly defined by the presence of abnormal and impaired
development, which manifests into a series of clinically relevant areas (or symptoms)
.Several diagnoses are combined into a single dimensional diagnosis, or ASD. Also,
two criteria of poor ASD quality in social interaction and communication.
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Except where otherwised noted, this item's license is described as Attribution 3.0 United States