Cystic fibrosis: physical exercise versus chest physiotherapy
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Date
2020-03-09
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
Cystic fibrosis (CF) may be a life threatening disease resulting in accumulation of
thick mucus which will affect the lungs , sudoriferous glands (sweet gland) and other
organs , due to chromosomal mutation in CFTR gene that encodes the CFTR protein
(cystic fibrosis trans membrane conductance regulator protein) this report is based on
a study that has been done on 12 children with CF that include work out program ,
were the physiotherapy and aerosol inhalation was stopped for a span of 17 days of
the program , but it didn't achieve to a major response.
Description
Cystic fibrosis a genetic abnormality which will effect lungs , reproductive tract ,
and gastrointestinal system .It's an autosomal recessive disease , a chromosomal
mutation in CF- associated gene that provide instruction to form CFTR protein (cystic
fibrosis trans membrane conductance regulator protein) , this protein pumps chloride
ions into different secretions this ion help draw water into the secretions which will
wind up thinning that out .The abnormalities in this protein leads to an accumulation
of thick , sticky , dehydrated mucus which will eventually clog the lungs and impair
the mucociliary clearance and also gives an appropriate environment for bacterial
growth
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Except where otherwised noted, this item's license is described as Attribution 3.0 United States