Agenesis of corpus callosum
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Date
2020-03-12
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
A study of fifty-six cases of agenesis of corpus callosum by the British neurological
surveillance unit (BNSU). (36 male), 37 were adults. Nearly two thirds had epilepsy;
half of the adult cases had intellectual impairment as estimated clinically, and a third a
psychiatric disorder. Nine cases (five adults) were apparently normal neurologically
Description
The corpus callosum is the main transverse tract of fibers that connects the two
cerebral hemispheres. Callosal efferent that originate in the cerebral cortex connect to
the contralateral hemisphere, integrating motor, sensory, and cognitive performances
of the brain. Initial formation of the axons that constitute the corpus callosum starts
anteriorly at the genu and continues through posteriorly to what eventually becomes
the body, a narrowed isthmus, and a widened splenium.
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