The Placebo Effect
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Date
2018-05-05
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
The aim of this report is to demonstrate the effects and mechanism of placebo, which is
something that’s supposed to act through a psychological mechanism. The placebo first came out
in 1811 and was first defined in the early 1960s as “any therapeutic procedure which has an
effect on a patient, symptom, syndrome or disease, but which is objectively without specific
activity for the condition being treated”
(1). The placebo is an aid to therapeutic suggestion. The
effect that’s produced may be psychological or physiological and it may produce a beneficial
result or toxic effects like headaches, diarrhea, nausea, vomiting, or even fatigue. The most
frequently used placebo is the sugar pill in drug trials, placebos can be and have been used for all
kinds of interventions, ranging from placebo pills for headaches and placebo doses for
postoperative wound pain to placebo vaccines for preventing cold and placebo surgeries for
alleviation of heart disease. The mechanism of action of the placebo is still unknown but it’s
believed to be either stimulus-expected by inert substances, or might be because of the
anticipation of one’s own automatic reactions to various situations. There are some factors that
may contribute in the effect of the placebo, like the patient’s attitudes, habits, educational
background, and personality types and characteristics. Other factors include the doses of the
placebo taken and the consistency, but the consensus was that no consistent placebo reactor was
out there
Description
The placebo effect is a remarkable phenomenon in which a placebo (a fake treatment), an
inactive substance (sugar, distilled water, or saline solution) can sometimes improve a patient's
condition simply because the person has the expectation that it will be helpful. If the person
expects the pill to do something, it’s possible the body’s chemistry can cause effects similar to
what a drug might have caused. The fact that the placebo effect is tied to expectations doesn’t
make it imaginary. Some studies show that there are actual physical changes that occur with the
placebo effect
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