Dopamine and its Relation to Age Related Physical Inactivity
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Date
2018-05-05
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
It's been forever known that dopamine is an important hormone but much attention has been
recently put towards its role as a neurotransmitter. Therefore, this present article aims first discuss
the role of dopamine as a neurotransmitter and then focus on its relationship with physical inactivity
and especially the age-related physical inactivity
Description
Dopamine is a monoamine neurotransmitter, meaning that it’s derived from an amino acid(1). It is a
catecholamine, meaning it contains a catechol nucleus(1). Dopamine is synthesized in areas of the
central and peripheral nervous systems, mainly in the hypothalamus, from the amino acid tyrosine,
it is converted to L-dopa, then decarboxylated to form dopamine(1). There are several areas of the
brain where dopamine neurons are concentrated. The largest are the midbrain, the hypothalamus,
olfactory bulb, and retina. There are also several major dopamine path-ways that carry dopamine
from these areas of concentration to other parts of the brain (2).
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Except where otherwised noted, this item's license is described as Attribution 3.0 United States
