Relation between chemotherapy and xerostomia
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Date
2018-04-18
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
the aim of this study is to determine how important chemotherapy is, and to
specifically highlight information regarding it is role in reducing salivary flow.
Description
Chemotherapy (chemo) is a type of treatment that includes a medication or
combination of medications to treat cancer. The goal of chemo is to stop or slow the
growth of cancer cells. Chemo is considered a systemic therapy. This means it may
affect your entire body. Chemo medications attack rapidly growing cancer cells, but
they can also affect healthy cells that grow rapidly. The effect of these medications on
normal cells often causes chemo side effects(1), in addition it has localized effects on
salivary glands, leading to xerostomia, which can be define as an overall redaction of
salivary output, there are many another causes for xerostomia include: aging as result
of continues loss of acinar cell, radiotherapy, Sjogren's syndrome (primary and
secondary). The chronic dryness of the mucosa in xerostomia leads to caries,
periodontal diseases, candidiasis and ascending(bacterial) sialadenitis(2), Dry mouth
can be a side effect of muscle relaxants and sedatives.(3) Other potential complications
include altered speech, changes to taste or smell, difficulty swallowing and
indigestion. Any of these side effects can impact patients’ overall eating and drinking
habits and nourishment
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Except where otherwised noted, this item's license is described as Attribution 3.0 United States