Multidrug resistant Tuberculosis
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Date
2019-04-01
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
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Tuberculosis remains a major cause of morbidity and
mortality globally, one of the causes are multidrug resistant
tuberculosis (MDR-TB). MDR-TB refers to tuberculosis that is
resistant to both rifampicin and isoniazid. Almost 20% of all
TB strains worldwide are resistant to at least one major TB
drug, approximately 10% are isoniazid monoresistant .
Multidrug resistant tuberculosis with additional resistance to
any fluoroquinolone (such as ofloxacin or moxifloxacin) and
also any one of the three second line injectable agents
(amikacin, capreomycin,kanamycin)is designated as
extensively drug resistant tuberculosis (1). Rapid diagnosis
and effective treatment are two of the most important
strategies tuberculosis(TB)control program to prevent
ongoing transmission of disease and to improve patient
outcomes
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