Characteristics of brain in Autism Spectrum Disorder

Mohammed, Amani (2020-02-17)

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and restricted repetitive behaviors (RRBs). The proportion of the adult population afflicted with ASD is estimated to be 2.4%– 9.9% childhood autism is broadly defined by the presence of abnormal and impaired development, which manifests into a series of clinically relevant areas (or symptoms) .Several diagnoses are combined into a single dimensional diagnosis, or ASD. Also, two criteria of poor ASD quality in social interaction and communication.

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Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder characterized by impaired social communication and restricted and repetitive behaviors (RRBs). Over the past decade, neuroimaging studies have provided considerable insights underlying neurobiological mechanisms of ASD. In this review, we introduce recent findings from brain imaging studies to characterize the brains of ASD across the human lifespan. Results of structural Magnetic Resonance Imaging (MRI) studies dealing with total brain volume, regional brain structure and cortical area are summarized. Using task-based functional MRI (fMRI), many studies have shown dysfunctional activation in critical areas of social communication and RRBs

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