Relation between Breast Cancer and Oral Contraceptives drug

Al Faitory, Fatma Ali (2020-03-12)

Breast cancer is uncontrolled growth of abnormal cells in the milk producing breast glands or in the passages (ducts) that carry milk to the nipples is the most common cancer of the breast,many risk factors have been identified for breast cancer, some of the most important risk factors such age in women over 50 years of age most cases of breast cancer occur, family history if a woman has a family or personal history of breast cancer, the risk of developing breast cancer increases, and additional risk factors: postmenopausal obesity, postmenopausal hormone replacement mammographic density, and alcohol consumption.The risk of Nulliparous and in those who delivered their first child after the age of 30 Pregnancy results in terminal differentiation of milkproducing luminal cells, removing them from the potential pool of cancer precursors. Obesity due to increased synthesis of estrogens in fat depots. Early age of menarche and late age of menopause (long reproductive period). High doses of exogenous estrogens used in the treatment of menopausal symptoms, atypical epithelial hyperplasia of breast. Carcinoma of endometrium of the other breast or functioning ovarian tumors


Oral contraceptives (OCs) use has been linked to increased risk of breast cancer (BC) are a concerning relationship as the incidence of breast cancer in the recent decades have been exponentially increasing around the globe,this occurs in breast tissue and is associated with various risk factors including breast cancer family history, excessive use of breast cancer medications, alcohol consumption, obesity, and elderly people,numerous research studies have shown an increased risk of breast cancer in women using oral contraceptives, especially in women with chronic history of use. Estrogen plays a leadership role in breast cancer pathophysiology. The aim of this report , we will discuss various research studies on the risk of breast cancer in women taking oral contraceptives, and whether or not birth control pills have a significant impact on breast cancer growth.

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