There is Difference Between Adult Male and Female in Urine Output After Lasix Consumption

Yousef, Omar (2022-09-04)


This current research aims to explore the difference between adult male and female in urine output after lasix consumption. Furosemide is a loop diuretic and has the ability to inhibit the sodium-potassium-s chloride (Na+/K+/2Cl-) cotransport of the ascending limb of the loop of Henle (NKCC2). The normal urine output (UO) is 800 to 2500 mL per day when there is a rapid reduction in its level pointing to a problem in the kidney. Several studies have reported whether gender has an effect on urine output after receiving a dose of furosemide, and other studies have ruled out this effect. In this study, 12 volunteers received 40 mg of furosemide intravenously and monitored the urine output for 6 hours continuously, and the results were recorded. There was no statistically significant difference in urine output for males and females according to P-value (=0.142) obtained from using the T-test, which was conducted using the Statistical Package for Social Sciences (SPSS).