Corpus Callosum and Epilepsy

Tuhami, Yara Masoud (2018-04-13)

The Corpus Callosum (CC) is the part of the mind that allows communication between the two hemispheres of the brain; therefor it is responsible for transmitting neural messages between both the right and left hemispheres.1 Studies have showed that the CC plays an important role in generalization of seizure activity; seeing how it is a commissure fiber bundle in the brain (largest forebrain commissure) that connects bilateral cerebral hemispheres


Corpus Callostomy is a palliative surgical procedure for the treatment of medically refractory epilepsy. In this procedure, the corpus callosum is cut through in an effort to limit the spread of epileptic activity between the two halves of the brain. The loss of connection between the two hemispheres leads to a major complication known as Split-Brain syndrome. Since the start of performing Callostomy as a treatment for epilepsy, several studies and researches have been done to better understand the phenomenon of split-brain syndrome. Moreover, the interesting changes in the brains of split-brain patients helped to form a better understanding of the perception and consciousness of the brain, and knowing the functional specialization of the cerebral hemispheres

Attribution 3.0 United States
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