Relationship between endometriosis and allergic disease
Endometriosis, a disease in which endometrial tissue grows outside the uterus (most commonly found inside the pelvis, ovaries, fallopian tubes and outside the womb. It can also be found in the bowel, the bladder, the intestines, the vagina and the rectum), affects an estimated 8–10% of reproductive age women, and may cause pelvic pain or infertility, although in many it is asymptomatic. A definitive diagnosis of endometriosis currently requires a laparoscopy, though growths can sometimes be detected during a manual pelvic exam or on ultrasound. The pathogenesis of endometriosis is not well understood. It is likely that endometrial cells from retrograde menstruation adhere to the peritoneal surfaces and proliferates, causing peritoneal inflammation
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While the underlying mechanisms of endometriosis are not yet understood, the available data to date suggest that endometriosis may have important long-term health consequences. Over recent decades, endometriosis has been associated with the risk of several chronic diseases, such as cancer, autoimmune diseases, asthma or allergic manifestations, and cardiovascular diseases. Because the underlying mechanisms for these relations are not known, a deeper understanding is needed as it may lead to novel discoveries on the causes or consequences of endometriosis. Our studies in this report have results that high rate of prevalence of allergic disease and other autoimmune disorder in patient surely diagnosed , where done by (Headquarters, Milwaukee, WI, USA) , Yale University Hospital (USA) and Ain shames university hospital respectively
