There is Difference Between Adult Male and Female in Urine Output After Lasix Consumption

Abstract

This current research aims to explore the difference between adult male and female in urine output after lasix consumption. Furosemide is a loop diuretic and has the ability to inhibit the sodium-potassium-s chloride (Na+/K+/2Cl-) cotransport of the ascending limb of the loop of Henle (NKCC2). The normal urine output (UO) is 800 to 2500 mL per day when there is a rapid reduction in its level pointing to a problem in the kidney. Several studies have reported whether gender has an effect on urine output after receiving a dose of furosemide, and other studies have ruled out this effect. In this study, 12 volunteers received 40 mg of furosemide intravenously and monitored the urine output for 6 hours continuously, and the results were recorded. There was no statistically significant difference in urine output for males and females according to P-value (=0.142) obtained from using the T-test, which was conducted using the Statistical Package for Social Sciences (SPSS).