The significance of gender differences on diuretics Pharmacodynamics

Abstract

Furosemide, a potent and selective loop diuretic, has been established in pharmacological development and clinical intervention to be required to achieve equal urine excretion rates in both sexes. Urine output was collected during the next 6 hours to determine pee volume female after 6 hour was 367.2 104.9 range from 216.0 to 518.4 ml and male after 6 hour was 468.0 114.02 range from 302.4 to 604.8ml urine output amount (P=0.142). There was no statistically significant difference in urine flow excretion rates between male and female patients across treatments. Our study's findings may be useful in the planning of future research projects or in patient education.