Myelin Water Fraction Change In Febrile Seizures
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Date
2019-02-03
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faculty of Basic Medical Science - Libyan International Medical University
Abstract
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Febrile seizures (FS) are seizure events occurring in children
older than 1 month that are associated with a fever not
caused by a central nervous system infection. They are the
most common cause of seizures in children younger than 5
years of age. While most children with FS do not develop
epilepsy. Simple FS is defined as a FS lasting less than 15
minutes and with no focality , while complex FS is defined as
a seizure lasting longer than 15 minutes, focal manifestations,
seizure recurrence in 24 hours[1]
, abnormal neurologic
examination findings, or history of afebrile seizures in a
parent or sibling. One tool for quantitating myelin content is a
novel imaging technique called mcDESPOT (multicomponentderived
equilibrium single-pulse observation of T1 and T2).
This quantitative magnetic resonance imaging (MRI)
technique estimates myelin water fraction (MWF)
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