Drug Absorption & Elimination

üAbsorption is a pharmacokinetic parameter that refers to the way a drug is absorbed from a pharmaceutical formulation into the bloodstream üMechanism of drug absorption: Passive diffusion (Nonionic diffusion, Facilitated Passive Diffusion, Active Transport, Endocytosis üFactors affecting drug absorption: •Drug specific factors affecting the drug absorption •Patient-specific factors affecting the drug absorption üDrug Elimination: Metabolism ( major occur the in Liver)+ Excretion(major occur in the kidney)