Topoisomerase II (TOP-2) is a promising molecular target for cancer therapy. Numerous antibiotics could interact with biologically relevant macromolecules and provoke antitumor potential. Herein, molecular docking studies ...

Background: Kidney stone disease (KSD) is a common disorder globally. Despite some improvements in detection methods and prevention strategies for kidney stones, but increase in KSD prevalence remain a problem. Objectives: ...

Globally, overweight and obesity are the fifth leading contributors to fatalities. According to the World Health Organization (WHO), overweight is defined as a body Mass Index (BMI)≥25, whereas obesity is a BMI≥30. There ...

The psychostimulant substances were used by medical students is a phenomenon partially well-known. The aim of present workwas to find the prevalenceof use and abuse of psychostimulant drugs among medical students.A ...

The heterocycle compounds, with their diverse functionalities, are particularly effective in inhibiting Janus kinases (JAKs). Therefore, it is crucial to identify the correlation between their complex structures and ...

The possibility of the preparation of free 1,1-dinitroethene was examined experimentally on the basis of procedures described earlier for other examples of 1-R-1-nitroethenes. It was found, that these types of protocols ...