Effect of Coffee in Improvement of Alzheimer's disease

Alshikhi, Sara Almabrouk Hamad (2018-04-14)

Caffeine, the principal alkaloid in coffee, tea, and energy drinks, is one of the most consumed psychoactive substances in the world  Studies suggest that coffee consumption affects health-related variables such as cancer ,exercise performance, diabetes, and blood pressure. Caffeine has been shown to affect multiple aspects of the central nervous system


The therapeutic benefits of coffee consumption against AD are apparent from various recent research studies  Research indicates that caffeine in the diet is linked to the reduction of hyperphosphorylated tau and can reduce the severity of AD symptoms  Caffeine is a non selective adenosine A2Areceptor antagonist  The A2A receptor is also expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release, making it a potential therapeutic target for the treatment of conditions such as insomnia, pain, depression, and Parkinson's disease

Attribution 3.0 United States
Except where otherwise noted, this item's license is described as Attribution 3.0 United States